How to apply Flexiseq®

How to apply Flexiseq
  1. Apply twice daily to the affected joint. It is recommended that you apply Flexiseq®; in the morning and at night to skin that is clean and dry
  2. Use enough gel to evenly cover the whole joint. For example, when treating the knee, we recommend using a gel length of around 7cm (roughly half the length of the Flexiseq® 50g tube)
  3. It is important to allow Flexiseq® to dry before covering. Failure to do so may impair the absorption of the product. The gel should dry after no more than 15 minutes. If drying time takes longer, just use a little less next time.

Are you Active?

If you experience joint pain or wear and tear as a result of an active lifestyle, Flexiseq Active may be the right treatment for you. Flexiseq Active contains a lighter formulation than the original award-winning product, providing a great introduction to joint pain relief if you are new to drug-free Joint Lubrication Therapy.

Are you active

Flexiseq® Frequently asked questions

It should not be applied directly over the bone, but to the soft tissue around it to allow it to penetrate through to the synovial fluid between the bones. It should also be allowed to dry, which may take about 10 minutes. The active component of the Flexiseq® gel will only begin to penetrate through the tissues once it has dried on the surface.


The pain relief appears to improve with repeated application. Whilst the manufacturers claim easing of symptoms can be experienced in as little as 2 days, realistically this would take 2 week but then still continues to improve gradually over 12 weeks. The onset of pain relief has been seen to be comparable to other pain relief products such as oral celecoxib.


Anybody with skin lesions or any dermatological conditions in the treatment area should not use Flexiseq® as its safety and efficacy has not been tested in such individuals. It should also not be used where they have already been prescribed another topical treatment, such as an NSAID gel.


No. Flexiseq® is classed as a medical device and is not included in the relevant section of the Drug Tariff. Therefore cannot be prescribed on NHS prescriptions.